COMPUTATIONAL STUDIES ON THE INHIBITOR SELECTIVITY OF HUMAN JAMM DEUBIQUITINYLASES RPN11 AND CSN5




Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during BCL-2 inhibition therapy

Introduction: Activating the aryl hydrocarbon receptor upon exposure to environmental pollutants promotes development of breast cancer stem cell (CSCs).BCL-2 family proteins protect cancer cells from the apoptotic hacklinkci.com effects of chemotherapeutic drugs.However, the crosstalk between AhR and the BCL-2 family in CSC development remains unin

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Signal of an autocorrelation low-coherence interferometer probing a layered object by a wave-field with wide angular spectrum

The effect of the width of the angular spectrum (numerical aperture) of a here broadband-frequency wave-field probing a layered object on the signal of an autocorrelation low-coherence interferometer (ALCI) under spatially coherent and incoherent illumination of the entrance pupil is considered.It is found that under incoherent illumination an incr

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